Research & Projects

Interactive surgical journey

Four translational phases, one validation path.

Select a phase to see connected A-STAR projects, methods, applications, and publications.

Active projects

Systems moving toward clinical use.

Project pages connect the evidence base above to the decision support, education, and validation tools currently under development.

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Status · validation

01 / Risk Stratification & Planning04 / Outcomes & Validation

MOSI

Metabolic & Obesity Staging Index

A staging algorithm and clinical audit platform for bariatric surgery, validated on 3,097 patients. MOSI scores patients across BMI, comorbidities, and severity to recommend procedures and target weight-loss tiers.

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Status · deployed

03 / Patient Journey & Education

SIRIS

Surgical-IRIS Education

SIRIS helps patients ask specialty-focused education questions, review Mayo Clinic resources, and prepare questions for their care team — bridging the information gap between booking and operation.

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Model cards

Tool-level intended use and readiness.

These cards summarize what each A-STAR system is for, what it accepts and returns, and where validation stands without overstating unfinished claims.

A-STAR model card

MOSI

Metabolic & Obesity Staging Index

Intended use: Pre-operative decision support for bariatric surgery candidate evaluation. Advisory only; clinical judgment remains with the treating surgeon.
Clinical phase: Risk stratification, planning, and outcomes validation
Input data: BMI and metabolic risk profile
Comorbidity burden
Prior bariatric procedure history
Procedure and outcomes variables used in validation workflows
Output: MOSI stage
Procedure category recommendation for review
Predicted total weight-loss tier
Audit-ready report
Model/pipeline: Rule-guided staging and decision-support workflow with prospective external validation in progress.
Validation status: Derivation and publication complete; prospective external multi-site validation is in progress.
Deployment readiness: Validation phase. Available as a clinical decision-support aid, not for autonomous use.
Limitations: Derived from Mayo Clinic data and not yet characterized across all populations or revisional surgery contexts.

Related publications

Mayo Obesity Staging and Indication (MOSI): A Novel Obesity Classification System in the Era of Medical, Endoscopic and Surgical Treatments

A-STAR model card

SIRIS

Surgical-IRIS Education

Intended use: Patient-facing education support for bariatric surgery preparation, question generation, and resource navigation.
Clinical phase: Patient journey and education
Input data: Natural language patient questions
Procedure context
Curated Mayo Clinic education resources
Output: Educational response
Relevant resource links
Suggested follow-up questions for the care team
Model/pipeline: Retrieval-augmented education workflow built around Mayo Clinic IRIS resources and surgical scope guardrails.
Validation status: Deployed with formal clinical evaluation and user-satisfaction study design in progress.
Deployment readiness: Public education deployment. Not a diagnostic tool and not a replacement for clinician consultation.
Limitations: Current scope is bariatric surgery education, English-language interactions, and non-urgent preparation questions.

Related publications

Online patient education resources in bariatric surgery: a systematic evaluation of quality, readability, transparency, and representation